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Men can benefit from hormone replacement therapy as part of a comprehensive and natural anti-aging program. As men age, the male hormones decline, referred to as “andropause”. Symptoms of andropause include decrease in muscle mass and muscle strength, increased body fat and lowered libido, accompanied by decrease in mental sharpness and decrease of overall energy […]

The andropausal symptoms can be helped and even reversed by the right supplementation of testosterone into the body. The idea of testosterone therapy is to restore testosterone to youthful levels to achieve optimal health and well-being. Testosterone is a vital hormone that plays an enormous role in the sex drive of both men and women. It is known to restore healthy sexual excitement and desire, which in turn improves attitude, relationships and well-being.

Testosterone therapy can help reverse the effects of hypogonadism, but it’s unclear whether testosterone therapy would have any benefit for older men who are otherwise healthy. Although some men believe that taking testosterone medications may help them feel younger and more vigorous as they age, few rigorous studies have examined testosterone therapy in men who have healthy testosterone levels — and some small studies have revealed mixed results. For example, in one study healthy men who took testosterone medications increased muscle mass but didn’t gain strength.

In the study, funded in part by drug maker Novo Nordisc, researchers looked the causes of death in almost 2,000 German men aged 20 to 79 years. The men with low testosterone at the start of study, which had an average follow up period of 7 years, had a more than 2.5 times greater risk of dying during the next 10 years compared with men with higher testosterone. These men tended to be older, fatter and had a greater prevalence of diabetes and high blood pressure than the men with higher testosterone levels, Haring said.

This difference was not explained by age, smoking, alcohol intake, level of physical activity or increased waist circumference (a risk factor for diabetes and heart disease), according to researcher author Robin Haring, a Ph.D. student from Ernst-Moritz-Arndt University of Greifswald, Institute for Community Medicine.

Low testosterone levels predicted increased risk of death from cardiovascular disease and cancer but not death of any other single cause, the study found.

Testosterone is the most important sex hormone (otherwise known as androgens) produced in the male body. It is the hormone that is primarily responsible for producing the typical adult male attributes. At puberty, testosterone stimulates the physical changes that characterize the adult male, such as enlargement of the penis and testes, growth of facial and pubic hair, deepening of the voice, an increase in muscle mass and strength, and growth in height. Throughout adult life, testosterone helps maintain sex drive, the production of sperm cells, male hair patterns, muscle mass and bone mass.

Testosterone is the most important sex hormone or androgen produced in men. The function of testosterone is primarily the producing the normal adult male characteristics. During puberty, testosterone stimulates the physical changes that constitute the attributes of the adult male.

Testosterone is truly a life source to the male body. Produced primarily in the testes by specialized Leydig cells, testosterone travels through the body via the bloodstream and binds to receptors on target tissues. There are testosterone receptors all over the body. As might be expected there are many in the genital area. However, the largest concentration is in the heart and brain. It is the receptor sites in the brain that create sexual desire which in turn trigger the release of nitric oxide to facilitate an erection.

The 203 men who met the criteria for depression had significantly lower total and free (not bound to proteins) testosterone levels than those who weren’t depressed. After controlling for other factors, such as cognitive scores, education level and body-mass index, the researchers concluded that men in the lowest quintile (20 percent) of free testosterone were three times more likely to have depression compared to those in the highest quintile.

The findings were published in the March issue of the Archives of General Psychiatry.

While more research is needed to determine how low hormone levels may be linked to depression risk, the study authors believe it may be caused by changes in the levels of neurotransmitters or hormones in the brain.

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