PHARMACOKINETICS
Testosterone esters are less polar than free testosterone. Testosterone esters in oil Injected intramuscularly are absorbed slowly from the lipid phase; thus, testosterone cypionate can be given at intervals of two to four weeks.

Testosterone in plasma is 98 percent bound to a specific testosterone-estradiol binding globulin, and about 2 percent is free. Generally, the amount of this sex-hormone binding globulin in the plasma will determine the distribution of testosterone between free and bound forms, and the free testosterone concentration will determine its half-life.

About 90 of a dose of testosterone is excreted in the urine as glucuronic and sulfuric acid conjugates of tesrtosterone and its metabolites; about 6 percent of a dose is excreted in the feces, mostly in the unconjugated form. Inactivation of testosterone occurs primarily in the liver. Testosterone is metabolized to various 17-keto steroids through two different pathways.

The half-life of testosterone cypionate when Injected intramuscularly is approximately eight days.

In many tissues the activity of testosterone appears to depend on reduction to dihydrotestost-
erone, which binds to cytosol receptor proteins. The steroid-receptor complex is transported to the nucleus where it initiates transcription events and cellular changes related to androgen action.

Most of the side effects are limited to HGH injections. HGH sprays or HGH supplements are considered to be milder forms of the product, and hence, are not associated with any adverse side effects. However, the indiscriminate use of any of the HGH product is linked to severe side effects and can result in complications.

Until recently, the only commercial testosterone products available contained methyltestosterone, a synthetic form of testosterone, in dosages only appropriate for men. Current studies, however, clearly show that testosterone is also an important hormone for women. Now, because of its increased popularity, there has been a rush by both pharmaceutical companies and compounding pharmacies to meet […]

Here is a list of drugs that cause Erectile Dysfunction / Male Impotence Drug Class Generic Brand Antihypertensives and Diuretics Hydrochlorothiazide Esidrix, Hydrodiuril, Inderide, Moduretic, Oretic, Lotensin Triamterine Maxide, Dyazide Furosdmide Lasix Chlorothalidone Hygrotone Bumetanide Bumex Guanfacine Tenex Methyldopa Aldomet Clonidine Catapres Verapamil Calan, Isoptin, Verelan Nifedipine Adalat, Procardia Hydralazine Apresoline Captopril Capoten Enalapril Vasotec […]

Erectile dysfunction (ED, “male impotence”) is a sexual dysfunction characterized by the inability to develop or maintain an erection of the penis sufficient for satisfactory sexual performance.

An erection occurs as a hydraulic effect due to blood entering and being retained in sponge-like bodies within the penis. The process is most often initiated as a result of sexual arousal, when signals are transmitted from the brain to nerves in the penis. Erectile dysfunction is indicated when an erection is difficult to produce. The most important organic causes are cardiovascular disease and diabetes, neurological problems (for example, trauma from prostatectomy surgery), hormonal insufficiencies (hypogonadism) and drug side effects ( Please click on the following link to view a list of drugs that can cause ED). Drugs That Cause ED .

Middle-aged? Tired? Not Interested in sex? Think only a new convertible could spark your desire?     Is male menopause a true medical condition or just a good punch line when you’re 50-something and not feeling quite yourself? You know, “Oh, that male menopause must’ve kicked in”? Could your doctor really diagnose male menopause, or […]

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