PHARMACOKINETICS
Testosterone esters are less polar than free testosterone. Testosterone esters in oil Injected intramuscularly are absorbed slowly from the lipid phase; thus, testosterone cypionate can be given at intervals of two to four weeks.

Testosterone in plasma is 98 percent bound to a specific testosterone-estradiol binding globulin, and about 2 percent is free. Generally, the amount of this sex-hormone binding globulin in the plasma will determine the distribution of testosterone between free and bound forms, and the free testosterone concentration will determine its half-life.

About 90 of a dose of testosterone is excreted in the urine as glucuronic and sulfuric acid conjugates of tesrtosterone and its metabolites; about 6 percent of a dose is excreted in the feces, mostly in the unconjugated form. Inactivation of testosterone occurs primarily in the liver. Testosterone is metabolized to various 17-keto steroids through two different pathways.

The half-life of testosterone cypionate when Injected intramuscularly is approximately eight days.

In many tissues the activity of testosterone appears to depend on reduction to dihydrotestost-
erone, which binds to cytosol receptor proteins. The steroid-receptor complex is transported to the nucleus where it initiates transcription events and cellular changes related to androgen action.

What is Human Growth Hormone? Human Growth Hormone (HGH) is one of the key hormones in the body which affects almost all the tissues including bones, muscles, skin tissue, liver, cardiac tissue, and the kidneys. However, it is essential to understand certain basic facts about the Human Growth Hormone—how it functions on the various organs […]

Increases Vitality – The Human Growth Hormone has the capacity to revive and revitalize the mind. It gives a tremendous boost to the memory, can repeal certain negative attitudes, viewpoints and expectations that are associated with ageing, and enhance concentration and cognition. It has an anti-depressive action, and promotes a sense of well-being and serenit

There is little information about how HGH assists in the management of Crohn’s disease; nevertheless, a rational explanation is available. HGH improves cell mediated response to antibodies and programs the immune system to respond by creating specific antigens. This is one of the reasons why HGH has been potentially beneficial in patients suffering from HIV/AIDS or from autoimmune disorders like lupus and arthritis. Secondly, HGH promotes organ restoration and helps in the growth and proliferation of intestinal tissue, which in turn, improves the patient’s clinical condition.

The Human Growth Hormone is a potential solution for patients suffering from IBS including Crohn’s disease, especially, in conjunction with dietary and life style changes.

The best treatment option for this problem is intra-articular administration of the human growth hormone. HGH is administered into the joint every 1 or 2 weeks. This allows the cells of the bone to change into cartilage cells. This process is defined as “Morphoangiogenesis”. This process was further studied by an orthopedic surgeon, Allan Dunn at Florida. He suggested that the growth hormone treatment must be performed when no other treatment is going on, as it could damage the growth hormone integrity and in turn the functionality.

In a study conducted by Johannson and his colleagues, at the Salgrenska University Hospital, it was found that HGH helps improve insulin sensitivity. The study design was a randomized double blind study involving 30 men between the age groups of 48 years to 66 years. These individuals were given low doses of HGH for a period of nine months, and great benefits of the same were observed. Glucose metabolism improved considerably, along with an average reduction of 18.1 % of abdominal fat, which has been considered to be a major cause of insulin resistance. The study concluded that HGH replacement therapy helps improve insulin sensitivity and assists in regulation of blood sugar levels.

HGH replacement has gained a considerable amount of momentum in recent times with the medical community and consumers realizing its benefits. The objective of HGH replacement is to stimulate an increase in the HGH levels secreted by the pituitary, and thereby help in combating certain adverse effects of aging. These symptoms can include, loss of lean muscle mass, increased fat composition of the body, disturbed sleep, reduced mental function and appearance of wrinkles on the skin. The HGH replacement process restores the youthful feeling into Hormone Replacement Therapy (HRT) patients and allows them to feel the same amount of vigor and energy as they did in their early 20s. There are different forms of HGH replacements which include: HGH sprays, HGH supplements, HGH injections and natural ways of stimulating the production of HGH.

Most of the side effects are limited to HGH injections. HGH sprays or HGH supplements are considered to be milder forms of the product, and hence, are not associated with any adverse side effects. However, the indiscriminate use of any of the HGH product is linked to severe side effects and can result in complications.

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